Protein_Domain

Part:BBa_K1075011

Designed by: Max Schelski   Group: iGEM13_Bonn   (2013-09-22)

Vinculin D1

This is the D1 Domain of mammalian Vinculin. It forms a tight Dimer with the ipaA peptide.

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, it is thought to function as one of the interacting proteins involved in anchoring F-actin to the membrane. Multiple alternatively-spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.[http://www.cell.com/retrieve/pii/0092867479903684]

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 56
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None